| Affected Tissue/Organ | Chromosome | Gene Product | Gene Symbol | # of Mutation Entry | Disease Name | Curator | |
Multi- tissue/organ |
colon, liver, ovary, prostate, stomach, uterus | 3 | catenin, beta-1 | CTNNB1 | 39 | cancer | Setsunan Univ. |
Multi- tissue/organ |
breast, ovary, stomach, thyroid, uterus | 16 | cadherin, epithelial | CDH1 | 105 | cancer | Setsunan Univ. |
Multi- tissue/organ |
eye, bladder, lung | 13 | RB1 Protein | RB1 | 229 | Retinoblastoma | Keio Univ. DMB. |
|
lung | 17 | tumor protein p53 | TP53 | 1232 | cancer | Mayo Clinic, USA |
|
lung | 17 | tumor protein p53 | TP53 | 6200 | cancer | Institut Curie (Paris), France |
|
lung | 17 | tumor protein p53 | TP53 | 6053 | cancer | Cariello N. F. et al., USA |
Multi- tissue/organ |
breast, ovary, esophagus, uterus, colon, prostate, skin, stomach, throat, pancreas | 17 | breast cancer, type 1 | BRCA1 | 540 | breast cancer | Keio Univ. |
Multi- tissue/organ |
breast, ovary, colon, prostate, pancreas, stomach, lung | 13 | breast cancer, type 2 | BRCA2 | 348 | breast cancer | Keio Univ. |